A paper detailing some of the work that I have been doing in Korea has recently been published in Angewandte Chemie.
The paper describes how high affinity host-guest complexes can be used in proteomic studies to enrich target proteins. The synthetic host-guest complexes have similar affinity to high affinity complexes typically used in the life sciences (Biotin-streptavidin). Unlike the protein based complexes, the synthetic system can be dissociated under mild conditions simply by adding a higher affinity guest.
Link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201611894/abstract
Advertisements
One thought on “New Paper: Enrichment of Specifically Labeled Protein Using an Immobilized Host Molecule”