New Paper: Enrichment of Specifically Labeled Protein Using an Immobilized Host Molecule

A paper detailing some of the work that I have being doing in Korea has recently been published in Angewandte Chemie.

The paper describes how high affinity host-guest complexes can be used in proteomic studies to enrich target proteins. The synthetic host-guest complexes have similar affinity to high affinity complexes typically used in the life sciences (Biotin-streptavidin). Unlike the protein based complexes, the synthetic system can be dissociated under mild conditions simply by adding a higher affinity guest.

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Link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201611894/abstract

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